A new drug is expected to be used to treat diabetic retinopathy

A new drug is expected to be used to treat diabetic retinopathy

December 03, 2018 Source: Xinhuanet

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An international research team has announced the development of a new drug that can be used to treat diabetic retinopathy, and has achieved efficacy in mouse experiments, which is expected to bring new options for the treatment of diabetic retinopathy in humans.

Diabetic retinopathy is a common complication of diabetes and a major cause of blindness in diabetes.

According to Jennifer Gamble, a researcher at the University of Australia and a professor at the Centennial Institute of Australia, diabetic retinopathy is mainly caused by damage to the blood-retinal barrier, and the integrity of the barrier depends on the tightness of the connection between capillary endothelial cells, if the endothelium Excessive or impaired gaps between cells can cause blood exudation in the capillaries of the retina to form lesions.

The new drug developed by Ganbul et al. is called CD5-2. The study found that the drug can repair the blood-retinal barrier and reduce vascular leakage. The effectiveness of the drug has been validated in mouse experiments, and the results were published in the journal Diabetes in Germany.

The researchers said in a statement that the new drug can be used alone or in combination with other existing therapies, and is expected to better treat diabetic retinopathy. They are currently pushing for clinical trials.

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