Key to the onset of myelodysplastic syndrome September 06, 2018 Source: Health News Network After 7 years of research, led by Professor Xiao Zhijian from the Institute of Hematology, Hematology Hospital, Chinese Academy of Medical Sciences, and Professor Huang Gang, a cancer biologist at the Cincinnati Children's Hospital Medical Center, revealed that hypoxia-inducible factor 幔°FIF1A) is myeloproliferative. The key molecule of the occurrence of abnormal syndrome (MDS), this discovery is expected to bring a breakthrough in the treatment of this malignant hematological tumor. The research paper was published online recently in the world's leading magazine on tumor discovery. Xiao Zhijian said that 40 to 60 gene mutations were found in patients with MDS using 2 generation sequencing technology. The research team first discovered HIF1A as a co-acting molecule in bone marrow cells of MDS patients with different gene mutations through transcriptomics and epigenomic analysis. Subsequently, in the construction of a series of transgenic mouse models carrying common gene mutations in different myelodysplastic syndromes, it was further confirmed that HIF1A dysfunction plays a central role in the development of myelodysplastic syndrome. By knocking out the HIF1A gene or applying a HIF1A inhibitor, the clinical characterization of the myelodysplastic syndrome in the mouse model can be reversed. These findings suggest that treatment with HIF1A as a target is expected to be a new therapeutic strategy for patients with MDS. Xiao Zhijian said that most of the current HIF1A small molecule inhibitors are not suitable for patients with MDS. The development of HIF1A-specific targeted drugs will be the next major topic for the research team. (Reporter Gan Beibei) White tea, belongs to the micro-fermented tea, old white tea is often prepared as medicine to practical, its medicinal properties are very good. It has the effect of moistening the lungs and protecting the liver. The production of white tea is special, after picking the fresh leaves, it is not killed, but only dried and processed by sun-drying. The buds and hairs of the finished tea are relatively intact, with white hairs showing and the fragrance of hairs overflowing; the soup color is clear, generally yellow-green, and the taste is light with a strong sweetness. The main production areas of white tea are in Fuding, Fujian, Zhenghe and Jinggu, Yunnan, and the more famous white teas are: white hairs silver needle, white peony, Shoumei, Fuding white tea and so on. White Tea Powder,White Matcha Tea,White Tea Powder Organic,White Matcha Powder Shaanxi Zhongyi Kangjian Biotechnology Co.,Ltd , https://www.zyplantextract.com
White tea is simpler than black tea and green tea in terms of production method. After being picked, it is directly dried or dried in the sun without any frying or twisting action. Because of the simplicity of the production process, white tea retains the nutrients in the tea leaves to a great extent. People who often drink white tea in the summer rarely get heatstroke. Experts believe that this is because white tea contains a variety of amino acids, which have the effect of reducing heat, dispelling heat and detoxifying.