Olaparib Product Name: Olaparib
Olaparib Synonyms: 4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one; 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]Methyl]-1(2H)-phthalazinone; KU 59436; AZD2281(olaparib)/AZD-2281; 1-(Cyclopropylcarbonyl)-4-[5-[(3, 4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin; Olaparid AZD2281; Olaparib (AZD2281, Ku-0059436); Olaparid
Olaparib CAS: 763113-22-0
Olaparib MF: C24H23FN4O3
Olaparib MW: 434.469
Olaparib EINECS: 1308068-626-2
Olaparib Product Categories: Inhibitor; Inhibitors; APIs; API
Olaparib Mol File: 763113-22-0. mol
Chemical Properties White Solid
Uses Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy.Â
Uses Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.Â
FAQ:Â
Q1: How is your product? /Â How could IÂ know your products quality? /Â Can you guarantee your quality?Â
A1: Thank you, yes, we have been run over 10 years in this market, our products has helped us won many bodybuilders and distributors, trustable quality you can get. Most of products meet USP/BP standard.Â
Q2: How to order? /Â Where can IÂ place the order?Â
A2: Kindly let me know the items you are looking for, quantity, and the destination country.Â
You confirm all details, and offer us purchasing order;Â
We send the detail price of our product and offer the suitable shipping method for reference;Â
You confirm the order and pay money 100% in advance and send us the detail address;Â
We arrange the shipment according to your requirements;Â
We offer after-sales service after you receive parcel.Â
Q3: Why should I order from you? / Can you give me a delivery guaranteed? / What are your advantages?Â
A3: High quality products at competitive price in quick delivery;Â
100% custom pass guaranteed;Â
Good after-sale service;Â
Flexible and Untraceable payment terms;Â
Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.Â
Q4: Can IÂ pay by PayPal? /Â How to pay? /Â Can you accept Credit Card?Â
A4: Payment Term are Western Union, Moneygram, Bitcoin and Bank Transfer; Sorry that we don't support PayPal and Credit Card. All these 4Â terms are convenient, and we could check the payment ASAP.Â
Olaparib Product Name: Olaparib
Olaparib Synonyms: 4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one; 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]Methyl]-1(2H)-phthalazinone; KU 59436; AZD2281(olaparib)/AZD-2281; 1-(Cyclopropylcarbonyl)-4-[5-[(3, 4-dihydro-4-oxo-1-phthalazinyl)Methyl]-2-fluorobenzoyl]piperazin; Olaparid AZD2281; Olaparib (AZD2281, Ku-0059436); Olaparid
Olaparib CAS: 763113-22-0
Olaparib MF: C24H23FN4O3
Olaparib MW: 434.469
Olaparib EINECS: 1308068-626-2
Olaparib Product Categories: Inhibitor; Inhibitors; APIs; API
Olaparib Mol File: 763113-22-0. mol
Chemical Properties White Solid
Uses Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy.Â
Uses Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.Â
FAQ:Â
Q1: How is your product? /Â How could IÂ know your products quality? /Â Can you guarantee your quality?Â
A1: Thank you, yes, we have been run over 10 years in this market, our products has helped us won many bodybuilders and distributors, trustable quality you can get. Most of products meet USP/BP standard.Â
Q2: How to order? /Â Where can IÂ place the order?Â
A2: Kindly let me know the items you are looking for, quantity, and the destination country.Â
You confirm all details, and offer us purchasing order;Â
We send the detail price of our product and offer the suitable shipping method for reference;Â
You confirm the order and pay money 100% in advance and send us the detail address;Â
We arrange the shipment according to your requirements;Â
We offer after-sales service after you receive parcel.Â
Q3: Why should I order from you? / Can you give me a delivery guaranteed? / What are your advantages?Â
A3: High quality products at competitive price in quick delivery;Â
100% custom pass guaranteed;Â
Good after-sale service;Â
Flexible and Untraceable payment terms;Â
Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.Â
Q4: Can IÂ pay by PayPal? /Â How to pay? /Â Can you accept Credit Card?Â
A4: Payment Term are Western Union, Moneygram, Bitcoin and Bank Transfer; Sorry that we don't support PayPal and Credit Card. All these 4Â terms are convenient, and we could check the payment ASAP.Â
Olaparib Ovarian Cancer Treatment Parp Inhibitors Olaparib 763113-22-0
Model NO.: 763113-22-0
Trademark: JC
Transport Package: Discreet Bag
Specification: 1kg
Origin: China
HS Code: 3001909099
Model NO.: 763113-22-0
Trademark: JC
Transport Package: Discreet Bag
Specification: 1kg
Origin: China
HS Code: 3001909099
 Olaparib Ovarian Cancer Treatment PARP inhibitors Olaparib 763113-22-0 Â
 Olaparib Ovarian Cancer Treatment PARP inhibitors Olaparib 763113-22-0 Â