What is YK11?
Full Name: (17-alpha,20E) 17,20-[(1-methoxyethylidene)bis(oxy)] 3-oxo-19-norpregna-4,20-diene 21-carboxylic acid methyl ester
Product Name: sarm yk11 1370003-76-1Â
Specification: ≥99% Â
Appearance: White fine Powder
Product Description
(17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel partial agonist. as well as by .
Â
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Â
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic  properties of YK11
Â
Fuction
It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as  differentiation  8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. So in research myostatin  are researched to find cures for muscle diseases.
Â
We expect YK11 to be more potent than SARM LGD in terms of overall growth and feel. At this time, we expect this to be the strongest SARM on the market at a regular dosing. While suppression can occur, we expect this product to have low androgenic properties and can be used by both men and women. From our experience with SARMs, we find there are less losses of on-cycle results than pro-, although typically not as potent. We do expect this product to have similar results as a moderately dosed Halodrol, without the alpha-male/androgenic feelings while on it.
Other SARMs
Name
CAS NO.
Usage
AICAR
2627-69-2
acts by entering nucleoside pools, significantly increasing levels of adenosineÂ
during periods of ATP breakdown
MK2866
841205-47-8
medical prescription for prevention of cachexia, atrophy, and sarcopenia andÂ
for Hormone or Testoserone Replacement Therapy.
MK-677
15972-10-0
Â
for the treatment of frailty in the elderly
LGD-4033
1165910-22-4
pharmacological profile similar to that of enobosarm, Ostarine,MK-2866
GW1516
317318-70-0
For obesity, diabetes, dyslipidemia and cardiovascular disease
Andarine(S4)
401900-40-0
partial agonist, intended mainly for treatment of benign prostatic hypertrophy
SR9009
1379686-30-2
under development at The Scripps Research Institute (TSRI),Â
increases the level of metabolic activity in skeletal muscles of mice
RAD140
1182367-47-0
New generation for gaining mass and cutting edges
YK11
431579-34-9
YK11: a SARM and myostatin inhibitor in one
Â
AC262356
870888-46-3
New SARMS
SR9011
1379686-29-9
New SARMS
S23
1010396-29-8
New SARMS
GW0724
317318-84-6
New SARMS
Hubei Zhaoke Bio-Chemical Co., Ltd.is a leading Chinese Pharmaceutical Ingredient supplier special in Steroi hormon powder,Test Propionat,Male sex enhancement powder and Anti-breast cancer powder.Such as Test enanthat,Test cypionat,Sus250, Anav,Nandr decanoat/phenypropionat,Methenolo acetat/enanthat,Trenb acetat/enanthat,Drostanol enanthat/Propionat,Bolde undecylenat/acetate...Our company supply preferential price and high quality products.We invest large fund and brains into R&D, developing new products and pioneering new technics, to meet the demand of the market. All the products from our plants are the fruit of out R&D department, reaching the advanced standard of domestic market, many of which reach the international standard.
Â
Product Name
Â
Product Name
1
Test enanthat/ TE/ Test en
22
Oxandr /Anav / OA
2
Test propionat/ TP/ Test pro
23
Oxymeth /Anadr / Oxy
3
Test cypionat/ TC/ Test cy
24
Stano /Winstr / ST
4
Test decanoae/ TD/ Test dec
25
Metand /Dana / DB
5
Test acetat/ TA/ Test ac
26
Trenb acetat/ TBA/ Trenb ac
6
Test phenylpropionat/ TPP
27
Trenb Enanthat/ TBE/ Trenb en
7
Test isocaproat/ TI
28
Drost Enanthat /DE
8
Test undecanoat/ TU
29
Drost Propionat /Master/ DP
9
Test base/ TB
23
Methen acetat / MA
10
Sus250Â /Â Test blend/ S250
31
Methen enanthae / ME
Â
Â
Â
Â
11
Nand decanoat /Â DEC
32
Mester /Provi
12
Nand Phenypropionat/ NP
33
17alpha-Methyl-Dros
13
Bold acetat / BA
34
17alpha-Methyl-1-test
14
Bold undecylenat /EQ/ BU
35
4-Chlorodehydromethyltest
15
Tamo Citrate /Nolv
36
4-Chlorotest acetate
16
Clomi Citrate /CC
37
Fluoxyn /Halotest
17
Anastr /Arimi
38
Sild citrate /Vig
18
Letr /Fema
39
Tada/Cis
19
Exeme /Aroma
40
Vardenafils /Levitras
20
L-Triiodothyr /T3
41
Finaste
21
GH 10IU/vial
42
CG 5000IU/vial
Q1:Can IÂ get some Test P samples?
A:Sure,we can supply the free sample,but the shipping cost be paid buy our customers.
Â
Q2:How to make orders?
A:Please send inquiry to us,after we come to an agreement,send payment via Western Union,Moneygram or Bank account,then we ship products out and give tracking number to you.
Â
Q3:How to delivery?
A:Pack shipped in 3Â days(Chinese holiday not included) after payment,usually ship via EMS,HKEMS,DHL,TNT,FedEx,UPS...
If there any troubles with shipping address,we will ship with specail safe and hidden packages,to guarantee you get packs without problems.
Â
Q4:Is there any discount?
A:Yes.The price is negotiable,If you order large quantity or some products together,you will get discount.
Â
Q5:What is the Minimum order quantity?
A:The Min. order quantity according to your request,10g,50g all is OK.
But the price according to the order quantity,the larger the order is,the better the price is.
Â
Q6:How to handle quality complaints?
A:Our quality control will reduce the quality to near zero,but if there is a quality problem caused by us,we will ship free products for replacement or refund your loss.
1. Top quality and factory price,a discount would be given when you make a large order.
2. Rich experienced in delivering,package will be reshipped if sent failed.Â
3. Enough Testostero Propionat stock ensure the prompt delivery time.Â
4. Good after-sales service,any of your question would be solved for the first as soon as possible.
5. Adhering to the principle of customer first conviction,we will provide the best and the most sincere services as possible as we can.
Â
What is YK11?
Full Name: (17-alpha,20E) 17,20-[(1-methoxyethylidene)bis(oxy)] 3-oxo-19-norpregna-4,20-diene 21-carboxylic acid methyl ester
Product Name: sarm yk11 1370003-76-1Â
Specification: ≥99% Â
Appearance: White fine Powder
Product Description
(17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel partial agonist. as well as by .
Â
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Â
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic  properties of YK11
Â
Fuction
It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as  differentiation  8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. So in research myostatin  are researched to find cures for muscle diseases.
Â
We expect YK11 to be more potent than SARM LGD in terms of overall growth and feel. At this time, we expect this to be the strongest SARM on the market at a regular dosing. While suppression can occur, we expect this product to have low androgenic properties and can be used by both men and women. From our experience with SARMs, we find there are less losses of on-cycle results than pro-, although typically not as potent. We do expect this product to have similar results as a moderately dosed Halodrol, without the alpha-male/androgenic feelings while on it.
Other SARMs
Name
CAS NO.
Usage
AICAR
2627-69-2
acts by entering nucleoside pools, significantly increasing levels of adenosineÂ
during periods of ATP breakdown
MK2866
841205-47-8
medical prescription for prevention of cachexia, atrophy, and sarcopenia andÂ
for Hormone or Testoserone Replacement Therapy.
MK-677
15972-10-0
Â
for the treatment of frailty in the elderly
LGD-4033
1165910-22-4
pharmacological profile similar to that of enobosarm, Ostarine,MK-2866
GW1516
317318-70-0
For obesity, diabetes, dyslipidemia and cardiovascular disease
Andarine(S4)
401900-40-0
partial agonist, intended mainly for treatment of benign prostatic hypertrophy
SR9009
1379686-30-2
under development at The Scripps Research Institute (TSRI),Â
increases the level of metabolic activity in skeletal muscles of mice
RAD140
1182367-47-0
New generation for gaining mass and cutting edges
YK11
431579-34-9
YK11: a SARM and myostatin inhibitor in one
Â
AC262356
870888-46-3
New SARMS
SR9011
1379686-29-9
New SARMS
S23
1010396-29-8
New SARMS
GW0724
317318-84-6
New SARMS
Hubei Zhaoke Bio-Chemical Co., Ltd.is a leading Chinese Pharmaceutical Ingredient supplier special in Steroi hormon powder,Test Propionat,Male sex enhancement powder and Anti-breast cancer powder.Such as Test enanthat,Test cypionat,Sus250, Anav,Nandr decanoat/phenypropionat,Methenolo acetat/enanthat,Trenb acetat/enanthat,Drostanol enanthat/Propionat,Bolde undecylenat/acetate...Our company supply preferential price and high quality products.We invest large fund and brains into R&D, developing new products and pioneering new technics, to meet the demand of the market. All the products from our plants are the fruit of out R&D department, reaching the advanced standard of domestic market, many of which reach the international standard.
Â
Product Name
Â
Product Name
1
Test enanthat/ TE/ Test en
22
Oxandr /Anav / OA
2
Test propionat/ TP/ Test pro
23
Oxymeth /Anadr / Oxy
3
Test cypionat/ TC/ Test cy
24
Stano /Winstr / ST
4
Test decanoae/ TD/ Test dec
25
Metand /Dana / DB
5
Test acetat/ TA/ Test ac
26
Trenb acetat/ TBA/ Trenb ac
6
Test phenylpropionat/ TPP
27
Trenb Enanthat/ TBE/ Trenb en
7
Test isocaproat/ TI
28
Drost Enanthat /DE
8
Test undecanoat/ TU
29
Drost Propionat /Master/ DP
9
Test base/ TB
23
Methen acetat / MA
10
Sus250Â /Â Test blend/ S250
31
Methen enanthae / ME
Â
Â
Â
Â
11
Nand decanoat /Â DEC
32
Mester /Provi
12
Nand Phenypropionat/ NP
33
17alpha-Methyl-Dros
13
Bold acetat / BA
34
17alpha-Methyl-1-test
14
Bold undecylenat /EQ/ BU
35
4-Chlorodehydromethyltest
15
Tamo Citrate /Nolv
36
4-Chlorotest acetate
16
Clomi Citrate /CC
37
Fluoxyn /Halotest
17
Anastr /Arimi
38
Sild citrate /Vig
18
Letr /Fema
39
Tada/Cis
19
Exeme /Aroma
40
Vardenafils /Levitras
20
L-Triiodothyr /T3
41
Finaste
21
GH 10IU/vial
42
CG 5000IU/vial
Q1:Can IÂ get some Test P samples?
A:Sure,we can supply the free sample,but the shipping cost be paid buy our customers.
Â
Q2:How to make orders?
A:Please send inquiry to us,after we come to an agreement,send payment via Western Union,Moneygram or Bank account,then we ship products out and give tracking number to you.
Â
Q3:How to delivery?
A:Pack shipped in 3Â days(Chinese holiday not included) after payment,usually ship via EMS,HKEMS,DHL,TNT,FedEx,UPS...
If there any troubles with shipping address,we will ship with specail safe and hidden packages,to guarantee you get packs without problems.
Â
Q4:Is there any discount?
A:Yes.The price is negotiable,If you order large quantity or some products together,you will get discount.
Â
Q5:What is the Minimum order quantity?
A:The Min. order quantity according to your request,10g,50g all is OK.
But the price according to the order quantity,the larger the order is,the better the price is.
Â
Q6:How to handle quality complaints?
A:Our quality control will reduce the quality to near zero,but if there is a quality problem caused by us,we will ship free products for replacement or refund your loss.
1. Top quality and factory price,a discount would be given when you make a large order.
2. Rich experienced in delivering,package will be reshipped if sent failed.Â
3. Enough Testostero Propionat stock ensure the prompt delivery time.Â
4. Good after-sales service,any of your question would be solved for the first as soon as possible.
5. Adhering to the principle of customer first conviction,we will provide the best and the most sincere services as possible as we can.
Â
Yk11 Yk-11 Sram Powder for Bodybuilding
Model NO.: CAS: 431579-34-9
Purity: 99.5%
Trademark: ZK
Transport Package: Specail and Safely Hidden Pack
Specification: USP
Origin: China
Model NO.: CAS: 431579-34-9
Purity: 99.5%
Trademark: ZK
Transport Package: Specail and Safely Hidden Pack
Specification: USP
Origin: China