Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0

Model NO.: 99%
CAS: 1134-47-0
Trademark: TJ
Transport Package: Camouflage Package
Specification: White powder
Origin: China
HS Code: 3003909010
Model NO.: 99%
CAS: 1134-47-0
Trademark: TJ
Transport Package: Camouflage Package
Specification: White powder
Origin: China
HS Code: 3003909010

Quick Detail:
Product Name: Baclofen
Synonyms: β-p-Chlorophenyl-GABA
CAS: 1134-47-0
MF: C10H12ClNO2
MW: 213.66
EINECS: 214-486-9
Product Categories:    Used as a skeletal muscle relaxation of the spinal cord
Mol File: 1134-47-0.mol

Description:
1) Baclofen (brand names Kemstro, Lioresal, Liofen, Gablofen, Lyflex, Beklo and Baclosan) is a derivative of gamma-aminobutyric Acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

(2) It is an agonist for the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups.

(3) A beneficial property of baclofen is that tolerance does not seem to occur to a significant degree - Baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment.

Application:
Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA).

A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.

Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0

Specifications:


Items Tested

Specification

Result

Characters

A white, crystalline powder or colorless crystals.

A white crystal.

Identification

IR should comply with the Reference Standard spectrum.
UV should comply with the Reference Standard spectrum.
An orange-red precipitate is performed.

IR complies with the Reference standard spectrum.
UV complies with the Reference standard spectrum.
An orange-red precipitate is performed.

Melting range

88 ~92 degree

89.8-90.2degree

Loss on Drying

Not more than 1.0%

0.22%

Readily carbonizable Substances

The resolution has no more color than Matching Fluid A.

Conform

Residue on ignition

Not more than 0.1%

0.02%

Heavy metals

Not more than 0.001%

Conform

Chloride

Conform

Conform

Assay (HPLC)

98.0%-102.0%

99.5%

Ordinary Impurities

≤1%

Conform

Reaction

Conform

Conform

Conclusion

Complies to USP31

Usage:
1. The product is a relaxant and antispasmodic agent acting on the skeletal muscle of spinal cord. Suitable for treating multiple-sclerosis bones spasms, spinal infection, degenerated muscle spasms; spinal cord trauma, and neoplastic muscle spasms.

2. It is currently the most effective muscle relaxants with least side effects.

Function:
Baclofen powder can be used as specific GABA-B receptor agonist. Muscle relaxant (skeletal). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. In addition, research has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.

Our adwantage:
1, High quality with competitive price:
    1) Standard: Enterprise Standard
    2) All Purity≥98%
    3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
    1) Parcel can be sent out within 24 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99%
    4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and      we have stock in there for transferring.

3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast                delivery meet their desire.
    2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our            responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the                customers.

Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0


 

Quick Detail:
Product Name: Baclofen
Synonyms: β-p-Chlorophenyl-GABA
CAS: 1134-47-0
MF: C10H12ClNO2
MW: 213.66
EINECS: 214-486-9
Product Categories:    Used as a skeletal muscle relaxation of the spinal cord
Mol File: 1134-47-0.mol

Description:
1) Baclofen (brand names Kemstro, Lioresal, Liofen, Gablofen, Lyflex, Beklo and Baclosan) is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

(2) It is an agonist for the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups.

(3) A beneficial property of baclofen is that tolerance does not seem to occur to a significant degree - Baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment.

Application:
Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA).

A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.

Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0

Specifications:


Items Tested

Specification

Result

Characters

A white, crystalline powder or colorless crystals.

A white crystal.

Identification

IR should comply with the Reference Standard spectrum.
UV should comply with the Reference Standard spectrum.
An orange-red precipitate is performed.

IR complies with the Reference standard spectrum.
UV complies with the Reference standard spectrum.
An orange-red precipitate is performed.

Melting range

88 ~92 degree

89.8-90.2degree

Loss on Drying

Not more than 1.0%

0.22%

Readily carbonizable Substances

The resolution has no more color than Matching Fluid A.

Conform

Residue on ignition

Not more than 0.1%

0.02%

Heavy metals

Not more than 0.001%

Conform

Chloride

Conform

Conform

Assay (HPLC)

98.0%-102.0%

99.5%

Ordinary Impurities

≤1%

Conform

Reaction

Conform

Conform

Conclusion

Complies to USP31

Usage:
1. The product is a relaxant and antispasmodic agent acting on the skeletal muscle of spinal cord. Suitable for treating multiple-sclerosis bones spasms, spinal infection, degenerated muscle spasms; spinal cord trauma, and neoplastic muscle spasms.

2. It is currently the most effective muscle relaxants with least side effects.

Function:
Baclofen powder can be used as specific GABA-B receptor agonist. Muscle relaxant (skeletal). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. In addition, research has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.

Our adwantage:
1, High quality with competitive price:
    1) Standard: Enterprise Standard
    2) All Purity≥98%
    3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
    1) Parcel can be sent out within 24 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99%
    4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and      we have stock in there for transferring.

3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast                delivery meet their desire.
    2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our            responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the                customers.

Active Pharmaceutical Ingredients Baclofen CAS 1134-47-0


 

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